Research · Cambridge, MA
Senior Scientist, Discovery
Lead medicinal chemistry efforts within a small-molecule program, from hit-to-lead through candidate nomination. You will work directly with structural biology, computational chemistry, and in vivo pharmacology.
What you will do
- Design and synthesize small molecules against an assigned target
- Interpret SAR from biochemical and cellular data
- Coordinate with structural biology on x-ray crystallography and cryo-EM
- Present at program reviews and contribute to regulatory documents
What you bring
- PhD in organic chemistry, medicinal chemistry, or related field
- Five or more years of industry medicinal chemistry experience
- Track record of contributing to development candidates
How we interview
- Introductory conversation. 30 minutes with the hiring manager to align on scope.
- Technical conversation. Two team members, 60 minutes, focused on how you think.
- Work sample. A task that mirrors a real piece of work for this role.
- Final conversation. How you work, what you need, and what we offer.
We aim to come back with a decision within two weeks of the final conversation.